Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 1.215


Transcription factors associated with POU5F1_SOX2{dimer}.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_312461590.476.7e-02Click!
SOX2chr3_+_182912769-0.476.9e-02Click!


Activity profile for motif POU5F1_SOX2{dimer}.p2.

activity profile for motif POU5F1_SOX2{dimer}.p2


Sorted Z-values histogram for motif POU5F1_SOX2{dimer}.p2

Sorted Z-values for motif POU5F1_SOX2{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1_SOX2{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_27508139 2.940 LOC643401
hypothetical protein LOC643401
chr4_+_74493918 2.509 ALB
albumin
chr17_+_24394281 2.359 PIPOX
pipecolic acid oxidase
chr6_-_138862273 2.348


chr10_+_7785360 2.241 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785235 2.171 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785290 2.168 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785331 2.094 ITIH2
inter-alpha (globulin) inhibitor H2
chr4_+_74493174 2.035 ALB
albumin
chr17_+_24394043 2.025 NM_016518
PIPOX
pipecolic acid oxidase
chr6_+_24465109 1.977 NM_181337
KAAG1
kidney associated antigen 1
chr4_+_100714995 1.906 MTTP
microsomal triglyceride transfer protein
chr6_+_132000134 1.818 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr4_+_74493331 1.763 ALB
albumin
chr3_+_186529376 1.665 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr8_-_17797127 1.565 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr4_+_74493266 1.562 ALB
albumin
chr16_-_54424517 1.541 NM_001025194
NM_001025195
NM_001266
CES1


carboxylesterase 1


chr4_+_74493218 1.423 ALB
albumin
chr21_+_41663853 1.395 MX2
myxovirus (influenza virus) resistance 2 (mouse)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
5.14 4.45e-03 GO:0072376 protein activation cascade
2.74 7.94e-06 GO:0007608 sensory perception of smell
2.69 2.46e-06 GO:0007606 sensory perception of chemical stimulus
1.93 2.97e-03 GO:0007600 sensory perception
1.60 4.34e-02 GO:0050877 neurological system process
1.30 2.70e-03 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.61 4.34e-02 GO:0044421 extracellular region part
1.46 6.40e-03 GO:0005576 extracellular region
1.32 1.20e-03 GO:0071944 cell periphery
1.31 2.36e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.80 1.62e-06 GO:0004984 olfactory receptor activity
1.99 1.04e-04 GO:0004930 G-protein coupled receptor activity
1.80 5.24e-05 GO:0004888 transmembrane receptor activity
1.60 7.92e-04 GO:0004872 receptor activity
1.54 6.00e-04 GO:0004871 signal transducer activity
1.54 6.00e-04 GO:0060089 molecular transducer activity